Varicocele is a more recognized cause of the important reasons for male infertility. In men about 10% to 15% of varicocele. Varicocele in infertile patients with combined 30% ~ 40%, varicocele and infertility are closely related. As early as over a hundred years ago, has been reported that varicocele is the cause of infertility, there is a group of 1294 cases of male infertility patients with observation, 39% of varicocele. However, most patients with varicocele does not affect fertility, according to statistics, 7% to 50% of cases of infertility in varicocele patients without surgical treatment, after the still birth. So, until today, the varicocele and fertility relationship is still a lot of controversy. Varicocele, about 50% to 80% of patients with abnormal semen examination, showed a low sperm count, activity is low, form abnormal. Varicocele caused infertility reasons: ¢Ù varicocele due to spermatic vein when the blood stasis, can cause increased temperature in the scrotum, testicular temperature rise 1 ¡æ ~ 2 ¡æ, the temperature continued to increase long-term, can affect the testes produce sperm, resulting in azoospermia and oligospermia; epididymis is not conducive to sperm maturation. However, spermatogenesis disorder occurs mainly in primary spermatocytes and the sperm cell stage. ¢Ú blood stasis, increased pressure within the spermatic vein, the lack of oxygen and nutrients affect the clearance of metabolites, thereby affecting spermatogenesis and mature. ¢Û left varicocele reflux of blood will be produced by adrenal glands and kidneys substances such as steroids, catecholamines, 5 - hydroxytryptamine, prostaglandin, etc. into the testes. 5 - HT is one of the toxins, toxic effects on the testis, prostaglandin so that reduction of testicular blood circulation, increase the epididymis contraction, is not conducive to sperm maturation and affect the sperm motility. ¢Ü varicocele testis interstitial cell damage, reduced testosterone secretion, blood testosterone levels also decreased, while the egg cell generation and promoting blood hormone (FSH) and interstitial cell stimulating hormone (ICSH) increased, endocrine disorders, as well as interfere with in spermatogenesis and mature.
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